| Author | Apinya Chanthakulchan |
| Call Number | AIT Thesis no.ISE-13-01 |
| Subject(s) | Electrospinning
|
| Note | A thesis submitted in partial fulfillment of the requirements for the degree of Master of Engineering in Industrial and Manufacturing Engineering, School of Engineering and Technology |
| Publisher | Asian Institute of Technology |
| Series Statement | Thesis ; no. ISE-13-01 |
| Abstract | Scaffold is a necessary vehicle for regeneration of tissue or organ in tissue engineering. Recently, the integration of electrospinning and rapid prototyping concepts ha s been investigated. The electrospinning jet can be controlled with the appropriated parameters to deposit the fibers on the desired location. In order to extend the potential of this concept, this research aimed to design and develop the electrospinning - based RP system to fabricate the controllable pattern scaffolds. The electrospinning - based RP system has been designed and the machine prototype was constructed . Sets of experiments have been conducted to identify the performance of the constructed machine. One - layer, two - layer and multi - layer fabrications were studied. The fiber propertie s and the control pattern capability were investigated . In addition, the process repeatability and reproducibility were studied in this research. From the experimental results, the machine prototype can cre ate the scaffolds in a pattern. The controllabili ty of created patterns is in a certain level. The fiber diameter size was about 150 to 170 μ m . However, the machine still has a vibration with a low magnitude, so the fibers were slightly shifted from the desired position. Moreover, the stacked fibers on t op of each other had effects from evaporation rate. The distance to produce electrospinning jet was low, so the evaporation time was too low. The deposited fibers were still in liquid on the collector. In addition, there was excess solution on the collecto r. That excess solution caused the flow of fibers when upcoming fibers were deposited. Hence, the condition to increase the evaporation rated should be studied. |
| Year | 2013 |
| Corresponding Series Added Entry | Asian Institute of Technology. Thesis ; no. ISE-13-01 |
| Type | Thesis |
| School | School of Engineering and Technology (SET) |
| Department | Department of Industrial Systems Engineering (DISE) |
| Academic Program/FoS | Industrial Systems Engineering (ISE) |
| Chairperson(s) | Pisut Koomsap |
| Examination Committee(s) | Huynh Trung Luong;Pitt Supaphol |
| Scholarship Donor(s) | RTG Fellowship |
| Degree | Thesis (M. Eng.) - Asian Institute of Technology, 2013 |