1 AIT Asian Institute of Technology

Wastewater reduction in the pharmaceutical industry : the effect of temperature on magnesium hydroxide paste process

AuthorPannee Boonsiri
Call NumberAIT Thesis no.EV-07-36
Subject(s)Pharmaceutical industry--Waste disposal

NoteA thesis submitted in partial fulfillment of the requirements for the degree of Master of Engineering in Environmental Engineering and Management.
PublisherAsian Institute of Technology
Series StatementThesis ; no. EV-07-36
AbstractPharmaceutical Industry is an important industry in Thailand to produce many kind of drug which it can save cost of the import medicine from abroad or foreign countries. The study industry is one of many plant of Government Pharmaceutical Organization. There are many products produced in this plant. Each product will be scheduled to produce from the same process operation. Magnesium Hydroxide process was scheduled for production during the research. The process was surveyed and observed to know the process running, material used, wastewater generated, temperature range, pH, product quality from the actual process operation. Suspended Solid in wastewaters was analyzed and the result of 1st process operation for 1st, 2nd, 3rd, 4th drainage is 170 mg/I, 50 mg/l, 120 mg/I and 120 mg/I respectively. The result of 2nd process operation for 1st, 2nd, 3rd, 4th drainage is 170 mg/l, 40 mg/l, 180 mg/I and 110 mg/I respectively. Total Dissolved Solid was analyzed and the result of 1st process operation for 1st, 2nd, 3rd, 4th drainage is 109,100 mg/l, 71,580 mg/l, 50,550 mg/l and 42,220 mg/l respectively. The result of 2nd process operation for 1st, 2nd, 3rd, 4th drainage is 81,200 mg/l, 86,120 mg/l, 55,820 mg/l and 37, 100 mg/l respectively.Lab-Scale experiment was set up at the proportion of MgSO4, NaOH and RO water are 430 ml, 270 ml, 1300 ml. The results give the trend of wastewater at different temperature that at 45 °C generated higher wastewater than at 55 °C and 65 °C and at temperature 65 °C generated lowest wastewater. From both experiment, Suspended Solid is lowest at temperature 55 °C and Total Dissolved Solid increase with temperature from 45 °C to 65 °C. Product quality is not different at difference temperature used in production. Heat consumption of boiler at 45 °C is 54,000 kcal/hr, 55 °C is 84,000 kcal/hr and 65 °C is 114,000 kcal/hr. The actual process is operated at between 50 °C to 60 °C when normal running of boiler. If we choose the temperature at 45 'C, we can save energy 35.71 % from at temperature 55 'C but it generated more wastewater, Suspended Solid and Total Dissolved Solid. If we choose the temperature at 65 'C, we have to pay more 26.32 % and the Suspended Solid and Total Dissolved Solid is not lower than at 55 'C but we can reduce wastewater volume.
Year2007
Corresponding Series Added EntryAsian Institute of Technology.--Thesis ;--no. EV-07-36
TypeThesis
SchoolSchool of Environment, Resources, and Development (SERD)
DepartmentDepartment of Energy and Climate Change (Former title: Department of Energy, Environment, and Climate Change (DEECC))
Academic Program/FoSEnvironmental Engineering (EV)
Chairperson(s)Thammarat Koottatep;
Examination Committee(s)Preeda Parkpian;Chettiyappan Visvanathan;
DegreeThesis (M.Eng.) - Asian Institute of Technology, 2007


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